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Abstract: Strains of mice vary in their susceptibility to ultra‐violet (UV) radiation‐induced skin tumors. Some strains of hairless mice (homozygous for the spontaneous Hrhr mutation) are particularly susceptible to these tumors. The skin tumors that develop in hairless mice resemble, both at the morphologic and molecular levels, UV‐induced squamous cell carcinomas (SCC) and their precursors in human...
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