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Key points
Tenascin‐X (TNX) is an extracellular matrix glycoprotein with anti‐adhesive properties in skin and joints. Here we report the novel finding that TNX is expressed in human and mouse gut tissue where it is exclusive to specific subpopulations of neurones.
Our studies with TNX‐deficient mice show impaired defecation and neural control of distal colonic motility that can be rescued with a...
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