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Autoantibodies against the 3 desmocollin (Dsc; Dsc1‐Dsc3) isoforms have been described in different pemphigus variants. Here, we developed state‐of‐the‐art detection systems for serum anti‐Dsc1, Dsc2 and Dsc1 IgG and IgA. These assays were applied in 5 different cohorts including pemphigus vulgaris (PV) patients with compatible direct immunofluorescence (IF) microscopy but no reactivity against desmogleins...
The Committee for Guidelines for the Management of Pemphigus was organized as one element of the Japanese Dermatological Association (JDA) and the Ministry of Health, Labour, and Welfare (MHLW) Research Project on Measures for Research Committee for Intractable Skin Disease. Pemphigus has been defined as a group of intractable autoimmune blistering diseases caused by anti‐desmoglein 1 and/or anti‐desmoglein...
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