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Objectives
DMT‐DALDA (H‐Dmt‐D‐Arg‐Phe‐Lys‐NH2; Dmt = 2′,6′‐dimethyltyrosine) is a selective mu opioid agonist. We sought to characterize efficacy, tolerance, dependence and side‐effect profile when given by continuous intrathecal infusion.
Materials and Methods
Adult male Sprague Dawley rats were prepared with chronic intrathecal catheters and osmotic mini‐pumps to deliver vehicle (saline), DMT‐DALDA...
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