Search results for: Norimichi Koitabashi

Items from 1 to 20 out of 39 results

article

Long‐term outcomes of intermediate coronary stenosis in patients undergoing hemodialysis after deferred revascularization based on fractional flow reserve

Takashi Nagasaka, Shiro Amanai, Yohei Ishibashi, Kazufumi Aihara, more

Catheterization and Cardiovascular Interventions > 100 > 6 > 971 - 978

Objectives This study aimed to assess the long‐term outcomes of patients undergoing hemodialysis (HD) after deferred revascularization based on fractional flow reserve (FFR). Background FFR is a practical technique for assessing the functional severity of intermediate coronary stenosis. Prior research has revealed a satisfactory outcome in patients after the deferral of percutaneous coronary intervention...

article

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury

Ryo Kawakami, Miki Matsui, Ayumu Konno, Ryosuke Kaneko, more

The Journal of Pathology > 255 > 4 > 362 - 373

Urinary fatty acid binding protein 1 (FABP1, also known as liver‐type FABP) has been implicated as a biomarker of acute kidney injury (AKI) in humans. However, the precise biological mechanisms underlying its elevation remain elusive. Here, we show that urinary FABP1 primarily reflects impaired protein reabsorption in proximal tubule epithelial cells (PTECs). Bilateral nephrectomy resulted in a marked...

article

Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice

Yogi Umbarawan, Mas Rizky A.A. Syamsunarno, Hideru Obinata, Aiko Yamaguchi, more

Metabolism > 2017 > 77 > C > 47-57

Myocardial contractile dysfunction in sepsis has been attributed mainly to increased inflammatory cytokines, insulin resistance, and impaired oxidative phosphorylation of fatty acids (FAs). However, precise molecular mechanisms underlying the cardiac dysfunction in sepsis remain to be determined. We previously reported major shift in myocardial energy substrates from FAs to glucose, and increased...

article

A 33-Year-Old Woman With Heart Failure Caused by Leriche Syndrome Concurrented to Aortitis Syndrome

Chikako Honda, Noriaki Takama, Hidemi Sorimachi, Makito Satou, more

Journal of Cardiac Failure > 2016 > 22 > 9(S) > S225

article

Cardiac Energetics Re-evaluated by in Vivo Visualization of ATP Levels

Norimichi Koitabashi, Masamichi Yamamoto, Takayuki Musashi, Mai Samejima, more

Journal of Cardiac Failure > 2015 > 21 > 10 Supplement > S174

article

NUCLEAR GLYCELALDEHYDE-3-PHOSPHATE DEHYDROGENASE SIGNALING MEDIATES PATHOLOGICAL CARDIAC HYPERTROPHY VIA P300 AND MYOCYTE ENHANCER FACTOR 2

Manling Zhang, Hideyuki Sasaki, Toshiaki Saitoh, Norimichi Koitabashi, more

Journal of the American College of Cardiology > 2015 > 65 > 10(S) > A2153

article

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress

Mirasari Putri, Mas Rizky A.A. Syamsunarno, Tatsuya Iso, Aiko Yamaguchi, more

Biochemical and Biophysical Research Communications > 2015 > 457 > 4 > 520-525

Hypothermia can occur during fasting when thermoregulatory mechanisms, involving fatty acid (FA) utilization, are disturbed. CD36/FA translocase is a membrane protein which facilitates membrane transport of long-chain FA in the FA consuming heart, skeletal muscle (SkM) and adipose tissues. It also accelerates uptake of triglyceride-rich lipoprotein by brown adipose tissue (BAT) in a cold environment...

article

Remarkable regression of massive deep vein thrombosis in response to intensive oral rivaroxaban treatment

Norimichi Koitabashi, Nogiku Niwamae, Tetsuya Taguchi, Yoshiaki Ohyama, more

Thrombosis Journal > 2015 > 13 > 1 > 1-6

Deep vein thrombosis (DVT) is a common disease and is associated with pulmonary embolism (PE). Proximal iliofemoral DVT may lead to severe PE and chronic venous insufficiency. The standard therapy for DVT is anticoagulant therapy using heparin and a vitamin K antagonist, but a recent clinical study showed that rivaroxaban, an oral Xa inhibitor, was comparable to standard therapy and had less bleeding...

article

Effects of adding intravenous nicorandil to standard therapy on cardiac sympathetic nerve activity and myocyte dysfunction in patients with acute decompensated heart failure

Shu Kasama, Takuji Toyama, Ryuichi Funada, Noriaki Takama, more

European Journal of Nuclear Medicine and Molecular Imaging > 2015 > 42 > 5 > 761-770

Purpose Nicorandil, an adenosine triphosphate-sensitive potassium channel opener, improves cardiac sympathetic nerve activity (CSNA) in ischemic heart disease or chronic heart failure. However, its effects on CSNA and myocyte dysfunction in acute heart failure (AHF) remain unclear. We investigated the effects of adding intravenous nicorandil to standard therapy on CSNA and myocyte dysfunction...

article

Periostin Cre-mediated Hypoxia-inducible Transfroming Growth Factor-β Receptor Deletion in Pulmonary Artery Prevents Pulmonary Arterial Hypertension in Mice

Mitsuru Seki, Norimichi Koitabashi, Hirokazu Arakawa, Masahiko Kurabayashi

Journal of Cardiac Failure > 2014 > 20 > 10 Supplement > S145

article

Fibroblast-specific TGFβ Receptor Inhibition Promotes Smooth Muscle Proliferation in Coronary Artery of Pressure-overloaded Mouse Heart

Norimichi Koitabashi, Masaru Obokata, Mitsuru Seki, Simon Conway, more

Journal of Cardiac Failure > 2014 > 20 > 10 Supplement > S150

article

Indoxyl Sulfate, a Uremic Toxin, Contributes Pathogenesis of Uremic Cardiomyopathy through Reduction of Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 2 Gene Expression

Masaru Obokata, Norimichi Koitabashi, Masahiko Kurabayashi

Journal of Cardiac Failure > 2013 > 19 > 10 Supplement > S158

article

Fatty Acid and Glucose Metabolism in Pressure Overloaded Mouse Heart –Radioisotope Based Quantitative Measurement-

Norimichi Koitabashi, Masaru Obokata, Aiko Yamaguchi, Syamsunarno Mraa, more

Journal of Cardiac Failure > 2013 > 19 > 10 Supplement > S142

article

Multiple papillary fibroelastomas of the aortic valve detected by real time three-dimensional transesophageal echocardiographic images

Koji Kurosawa, Kazuaki Negishi, Rieko Tateno, Norimichi Koitabashi, more

Journal of Cardiology Cases > 2013 > 8 > 1 > e9-e12

Papillary fibroelastoma (PFE) is a well-known primary cardiac tumor, but multiple PFEs are rare. We report an interesting case with multiple PFEs that were clearly demonstrated and evaluated with real time three-dimensional (RT3D) transesophageal echocardiography (TEE). A 77-year-old woman was referred to our institution with a diagnosis of osteoarthritis of the hip. Transthoracic echocardiography...

article

SERUM FATTY ACID BINDING PROTEIN 4 IS AN EARLY MARKER FOR ACUTE MYOCARDIAL INFARCTION

Yoshiaki Ohyama, Tatsuya Iso, Kuniko Masuda, Shuntaro Tamura, more

Journal of the American College of Cardiology > 2013 > 61 > 10(S) > E191

article

INTEGRATED AREA DESATURATION INDEX IS MAJOR PREDICTOR OF FATAL CARDIOVASCULAR EVENTS IN PATIENTS WITH HEART FAILURE AFTER ADAPTIVESERVO VENTILATION THERAPY

Noriaki Takama, Syuntaro Tamura, Kuniko Masuda, Makoto Murata, more

Journal of the American College of Cardiology > 2013 > 61 > 10(S) > E773

article

Catecholamine-induced Cardiac Fibrosis is Paradoxically Controlled by TGFβ Signaling

Norimichi Koitabashi, Masaru Obokata, Masashi Arai, David Kass, more

Journal of Cardiac Failure > 2012 > 18 > 10 Supplement > S189

article

Indoxyl Sulfate, a Uremic Toxin, Exaggerates Cardiac Connective Tissue Growth Factor Expression

Masaru Obokata, Norimichi Koitabashi, Masashi Arai, Masahiko Kurabayashi

Journal of Cardiac Failure > 2012 > 18 > 10 Supplement > S152

article

RGS2 is a primary terminator of β2-adrenergic receptor-mediated Gi signaling

Khalid Chakir, Weizhong Zhu, Sharon Tsang, Anthony Yiu-Ho Woo, more

Journal of Molecular and Cellular Cardiology > 2011 > 50 > 6 > 1000-1007

Two major β-adrenergic receptor (βAR) subtypes, β ₁ AR and β ₂ AR, are expressed in mammalian heart with β ₁ AR coupling to G _s and β ₂ AR dually coupling to G _s and G _i proteins. In many types of chronic heart failure, myocardial contractile response to both β ₁ AR and β ₂ AR stimulation is severely impaired. The dysfunction...

article

Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5

Manling Zhang, Eiki Takimoto, Steven Hsu, Dong I. Lee, more

Journal of the American College of Cardiology > 2010 > 56 > 24 > 2021-2030

We tested the hypothesis that bi-directional, gene-targeted regulation of cardiomyocyte cyclic guanosine monophosphate–selective phosphodiesterase type 5 (PDE5) influences maladaptive remodeling in hearts subjected to sustained pressure overload.PDE5 expression is up-regulated in human hypertrophied and failing hearts, and its inhibition (e.g., by sildenafil) stimulates protein kinase G activity,...

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Keywords

HYPERTROPHY (4)
PROTEIN KINASE G (4)
HEART FAILURE (3)
PRESSURE OVERLOAD (3)
CALCIUM (2)
CARDIAC FUNCTION (2)
FATTY ACID (2)
GENE EXPRESSION (2)
MYOCYTE (2)
SERCA2 (2)
SILDENAFIL (2)
ACUTE HEART FAILURE (1)
ACUTE KIDNEY INJURY (1)
ANGIOTENSIN II (1)
ANTICOAGULATION (1)
AORTIC VALVE (1)
BROWN ADIPOSE TISSUE (1)
CALCINEURIN (1)
CARDIAC FIBROBLASTS (1)
CARDIAC HYPERTROPHY (1)
CARDIOMYOCYTE CONTRACTILITY (1)
CD36 (1)
CYCLIC GMP (1)
CYCLIC NUCLEOTIDES (1)
CYTOKINES (1)
DEEP VEIN THROMBOSIS (1)
DEFERRED REVASCULARIZATION (1)
DENT DISEASE (1)
ENERGY METABOLISM (1)
EXTRACELLULAR MATRIX (1)
FRACTIONAL FLOW RESERVE (1)
GALPHAQ (1)
GENE TRANSCRIPTION FACTOR (1)
GI PROTEINS (1)
GLUCOSE (1)
HEMODIALYSIS PATIENTS (1)
HEMODYNAMICS (1)
HYPOTHERMIA (1)
ILIAC VEIN COMPRESSION (1)
IN VIVO GENE TRANSFER (1)
INTERMEDIATE CORONARY STENOSIS (1)
LIPOPOLYSACCHARIDE (1)
LIVER INJURY (1)
LUCIFERASE ASSAY (1)
MEGALIN (1)
MOUSE MODELS (1)
MULTIPLE PAPILLARY FIBROELASTOMA (1)
NATRIURETIC PEPTIDE (1)
NICORANDIL (1)
OXIDATIVE STRESS (1)
PDE5 (1)
PDE5A (1)
PHOSPHODIESTERASE (1)
PHOSPHODIESTERASE 5A (1)
PHOSPHODIESTERASE-5 (1)
PHOSPHOLAMBAN (1)
PROTEIN REABSORPTION (1)
PROXIMAL TUBULE EPITHELIAL CELLS (1)
REAL TIME THREE-DIMENSIONAL TRANSESOPHAGEAL ECHOCARDIOGRAPHY (1)
RECEPTOR-OPERATED CATION CHANNEL (1)
REMODELING (1)
REVIEW (1)
RGS2 (1)
RIVAROXABAN (1)
RNA INTERFERENCE (1)
SARCOPLASMIC RETICULUM (1)
SEPSIS (1)
SILDENAFIL EXPRESSION (1)
SKELETAL MUSCLE (1)
SP1 (1)
STRESS RESPONSE KINASE (1)
SYMPATHETIC NERVOUS SYSTEM (1)
THROMBUS REGRESSION (1)
TRANSCRIPTION REGULATION (1)
TRANSGENIC MOUSE MODELS (1)
TRPC (1)
TRPC6 (1)
TUMOR NECROSIS FACTOR-Α (1)
URINARY FABP1 (1)
VASCULAR (1)
VENTRICULAR REMODELING (1)
Β-ADRENERGIC RECEPTOR (1)
Β2-ADRENERGIC RECEPTOR (1)
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Elsevier (34)
Springer (3)
Wiley (2)

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Search results for: Norimichi Koitabashi

Long‐term outcomes of intermediate coronary stenosis in patients undergoing hemodialysis after deferred revascularization based on fractional flow reserve

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury

Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice

A 33-Year-Old Woman With Heart Failure Caused by Leriche Syndrome Concurrented to Aortitis Syndrome

Cardiac Energetics Re-evaluated by in Vivo Visualization of ATP Levels

NUCLEAR GLYCELALDEHYDE-3-PHOSPHATE DEHYDROGENASE SIGNALING MEDIATES PATHOLOGICAL CARDIAC HYPERTROPHY VIA P300 AND MYOCYTE ENHANCER FACTOR 2

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress

Remarkable regression of massive deep vein thrombosis in response to intensive oral rivaroxaban treatment

Effects of adding intravenous nicorandil to standard therapy on cardiac sympathetic nerve activity and myocyte dysfunction in patients with acute decompensated heart failure

Periostin Cre-mediated Hypoxia-inducible Transfroming Growth Factor-β Receptor Deletion in Pulmonary Artery Prevents Pulmonary Arterial Hypertension in Mice

Fibroblast-specific TGFβ Receptor Inhibition Promotes Smooth Muscle Proliferation in Coronary Artery of Pressure-overloaded Mouse Heart

Indoxyl Sulfate, a Uremic Toxin, Contributes Pathogenesis of Uremic Cardiomyopathy through Reduction of Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 2 Gene Expression

Fatty Acid and Glucose Metabolism in Pressure Overloaded Mouse Heart –Radioisotope Based Quantitative Measurement-

Multiple papillary fibroelastomas of the aortic valve detected by real time three-dimensional transesophageal echocardiographic images

SERUM FATTY ACID BINDING PROTEIN 4 IS AN EARLY MARKER FOR ACUTE MYOCARDIAL INFARCTION

INTEGRATED AREA DESATURATION INDEX IS MAJOR PREDICTOR OF FATAL CARDIOVASCULAR EVENTS IN PATIENTS WITH HEART FAILURE AFTER ADAPTIVESERVO VENTILATION THERAPY

Catecholamine-induced Cardiac Fibrosis is Paradoxically Controlled by TGFβ Signaling

Indoxyl Sulfate, a Uremic Toxin, Exaggerates Cardiac Connective Tissue Growth Factor Expression

RGS2 is a primary terminator of β2-adrenergic receptor-mediated Gi signaling

Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5

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