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Cyclin D1 is aberrantly expressed in many types of cancers, including breast cancer. High levels of cyclin D1b, the truncated isoform of cyclin D1, have been reported to be associated with a poor prognosis for breast cancer patients. In the present study, we used siRNA to target cyclin D1b overexpression and assessed its ability to suppress breast cancer growth in nude mice. Cyclin D1b siRNA effectively...
Methodology of automatic generation of test cases based on Model Driven Architecture is proposed, and its design and implementation have be done. The process of generating test cases is that a platform-independent model is converted into a platform-independent test model through level conversion, and the platform-independent test model is converted into the corresponding test cases through vertical...
An inverted index structure of path that based on domain ontology is proposed in this paper. The all of distinct entities in domain ontology are indexed; and for each distinct entity an inverted list, storing the entity and the identifiers of the path containing the entity, and experimental results show that the index structure is more suitable for the query of multiple keywords and it can eliminate...
Dry point of aviation kerosene in the atmospheric distillation column is a very important process value for quality controlling. But unfortunately few on-line hardware sensors are available to this value or such sensors are difficult to maintain. This paper adopts a novel method based on least squares support vector machine (LS-SVM) regression to implement on-line estimation of aviation kerosene dry...
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