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Anaerobic bacteria, such as Clostridium and Salmonella, can selectively invade and colonize in tumor hypoxic regions (THRs) and deliver therapeutic products to destroy cancer cells. Herein, we present an anaerobe nanovesicle mimic that can not only be activated in THRs but also induce hypoxia in tumors by themselves. Moreover, inspired by the oxygen metabolism of anaerobes, we construct a light‐induced...
Anaerobe Bakterien dienten als Vorlage für ein Wirkstofftransportsystem, das von Q. D. Shen, Z. Gu et al. in der Zuschrift auf S. 2632 ff. beschrieben wird. Die biomimetischen Nanovesikel sind in Zellen mit einer normalen physiologischen Redox‐ und Sauerstoffbilanz stabil. Bei Lichteinstrahlung brechen sie auf und entfalten ihre duale synergistische Antikrebswirkung mit erhöhter therapeutischer Wirkung...
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