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BACKGROUND
To the authors' knowledge, optimal adjuvant approaches for resected duodenal adenocarcinoma are not well established. Given the significant risk of locoregional disease recurrence, there may be a subset of patients who demonstrate an improvement in overall survival (OS) from the addition of radiotherapy (chemoradiotherapy [CRT]) to an adjuvant chemotherapy regimen.
METHODS
Patients with...
BACKGROUNDThe role of adjuvant chemotherapy (AC) in the treatment of small bowel adenocarcinoma is poorly defined. Previous analyses have been limited by small sample sizes and have failed to demonstrate a survival advantage.
METHODSPatients with resected small bowel adenocarcinoma (American Joint Committee on Cancer [AJCC] pathologic stage I‐III) who were receiving AC (n = 1674) or surgery alone...
BACKGROUNDThe literature investigating pancreatic invasive intraductal papillary mucinous neoplasm (IPMN) has largely come from small institutional studies, preventing adequately powered comparisons of adjuvant therapy versus surgery alone (SA) within specific patient subgroups.
METHODSPatients with resected, stage I through IV, invasive IPMN and conventional pancreatic ductal adenocarcinoma (PDAC)...
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