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Anti-glycation activity of gold nanoparticles (GNPs) has been reported for the first time. Nonenzymatic glycation of α-crystallin leads to formation of cataract, or opaque aggregate of proteins. In this article we report prevention of glycation of α-crystallin by conjugation with GNPs. Formation of advanced glycosylic end products is prevented even if a strong glycating agent such as fructose is used...
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