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Transgenic mice that express mutant human amyloid precursor protein (APP Tg2576 ) develop β-amyloid (Aβ) plaques throughout the cortex starting at 10-12 months of age. We examined the neurochemical profile of APP Tg2576 mice using in vitro and in vivo magnetic resonance spectroscopy (MRS); gross abnormalities using magnetic resonance...
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