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Subtypes of P2Y receptors are well characterized with respect to their agonist profile but little is known about differences in their intracellular signalling properties. When expressed in Xenopus oocytes, both P2Y 2 and P2Y 6 receptors effectively couple to endogenous Ca 2+ -dependent Cl - -channels. However, only P2Y 2 receptors increased currents mediated...
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