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Phosphorylation is a crucial post-translational modification, which regulates almost all cellular processes in life. It has long been recognised that protein phosphorylation has close relationship with diseases, and therefore many researches are undertaken to predict phosphorylation sites for disease treatment and drug design. However, despite the success achieved by these approaches, no method focuses...
Subcellular location of a protein is one of the key functional characters as proteins must be localized correctly at the subcellular level to have normal biological function. In this work, a novel hybrid-classifier prediction method has been introduced, which uses evolutionary information and sequence-order information to improve prediction performance. Prediction results on different data sets show...
Subcellular location of a protein is one of the key functional characters as proteins must be localized correctly at the subcellular level to have normal biological functions. In this paper, all motifs in PROSITE were examined and those that are indicative to eukaryotic protein subcellular localizations were picked out. A corresponding motif module was built and combined to our former work: LOCSVMPSI...
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