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Polycyclic aromatic hydrocarbons (PAH) are ubiquitous global pollutants. Limited studies suggested that PAH may interfere with thyroid function in animals, but little is known about humans. A population of 480 Chinese males was recruited. Using LC–MS/MS, four urinary metabolites of PAH including 1-hydroxynaphthalene (1-N), 2-hydroxynaphthalene (2-N), 1-hydroxypyrene (1-P) and 2-hydroxyfluorene (2-F)...
Many pesticides possess hormonal activities and have been classified as endocrine disrupting chemicals. Synthetic pyrethroids are one kind of the most common pesticides used in the world. In the present study, we explored the association between serum reproductive hormone levels and urinary creatine (CR) adjusted concentration of 3-phenoxybenzoic acid (3-PBA), a general metabolite of pyrethroids,...
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