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The percentages of healthy subjects carrying ampicillin- and cefaclor-resistant streptococci in saliva were 52% (27 of 52 subjects) and 100%, respectively. From the sequencing results of pbp1a, 2x, 2b genes, Streptococcus mitis including both ampicillin-resistant and -susceptible strains (a total of 13 strains) were divided into 5 groups. The highly resistant strains had multiple mutations in all...
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