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We report that a lactoperoxidase (LPO) metabolite derived from nitrite (NO 2- ) catalyses one-electron oxidation of biological electron donors and antioxidants such as NADH, NADPH, cysteine, glutathione, ascorbate, and Trolox C. The radical products of the reaction have been detected and identified using either direct EPR or EPR combined with spin trapping. While LPO/H 2 O ...
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