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Recent studies demonstrated the neuro-protective role of H2S during a moderate brain injury. In this study, we employed a rat cerebral I/R model with longer time global ischemia and investigated the effect of H2S on a much more severe cerebral injury, as well as the underlying mechanisms. After a 24h I/R, administration of NaHS, an exogenous donor for H2S, at the dose of 0.2 or 0.4mmol/kg significantly...
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