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Purpose
To investigate the influence of transcytolemmal water exchange on estimates of tissue microstructural parameters derived from diffusion MRI using conventional PGSE and IMPULSED methods.
Methods
Computer simulations were performed to incorporate a broad range of intracellular water life times τin (50–∞ ms), cell diameters d (5–15 μm), and intrinsic diffusion coefficient Din (0.6–2 μm2/ms)...
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