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Continuous production of nisin in laboratory media and whey permeate was investigated using a packed-bed bioreactor. Lactococcus lactis subsp. lactis ATCC 11454 was immobilized by natural attachment to fibre surfaces and entrapment in the void volume within spiral wound fibrous matrix. The inoculated bioreactor was fed M17 medium and effect of pH, temperature, dilution rate, and substrate concentrations...
Fermentation kinetics of butyrate production from glucose and xylose by Clostridium tyrobutyricum ATCC 25755 immobilized in a fibrous-bed bioreactor at pH 6.0 and 37 o C were studied. Fermentation with glucose as the main carbon source gave higher cell biomass production and reactor productivity compared with xylose fermentation, probably due to the extra energetic requirement for cell growth...
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