The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
scFv (single-chain Fv fragment) is the gene engineered antibody employed widely in at present. Recently there have been some progress on colorectal cancer diagnosis and treatment-oriented with scFv as carrier, but it is differential on affinity and anti-tumor activity of scFv with that of derived factor. Proper linker could make scFv have more suitable biological activity on clinical application....
Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and functions. However, their in genomes is unknown because current detection methods can miss many occurrences, mistaking random repeats as circular permutation. Here we develop a method for detecting circularly permuted...
An effective potential function is critical for protein structure prediction and folding simulation. For simplified models of proteins where coordinates of only Ca atoms need to be specified, an accurate potential function is important. Such a simplified model is essential for efficient search of conformational space. In this work, we present a formulation of potential function for simplified representations...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.