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Direct administration of drugs and genes to the lungs by pulmonary delivery offers a potential effective therapy for lung cancers. In this study, combined doxorubicin (DOX) and Bcl2 siRNA was employed for cancer therapy using polyethylenimine (PEI) as the carrier of Bcl2 siRNA. Most of the DOX and siRNA possessed high cellular uptake efficiency in B16F10 cells, which was proved by FCM and CLSM analysis...
In pH 5.5 phosphate buffer solution, N-n-undecyl-N′-(sodium-p-amino-benzenesulfonate) thiourea (UPT) produced a pair of redox peaks on the bare glassy carbon electrode. At the multi-walled carbon nanotube (MWNT) modified electrode, the electrochemical behavior of UPT enhanced greatly. In the presence of bovine serum albumin (BSA), the peak currents of UPT decreased linearly due to the formation of...
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