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Histopathology image classification can provide automated support towards cancer diagnosis. In this paper, we present a transfer learning-based approach for histopathology image classification. We first represent the image feature by Fisher Vector (FV) encoding of local features that are extracted using the Convolutional Neural Network (CNN) model pretrained on ImageNet. Next, to better transfer the...
Bone texture characterization is important for differentiating osteoporotic and healthy subjects. Automated classification is however very challenging due to the high degree of visual similarity between the two types of images. In this paper, we propose to describe the bone textures by extracting dense sets of local descriptors and encoding them with the improved Fisher vector (IFV). Compared to the...
Developing segmentation techniques for overlapping cells has become a major hurdle for automated analysis of cervical cells. In this paper, an automated three-stage segmentation approach to segment the nucleus and cytoplasm of each overlapping cell is described. First, superpixel clustering is conducted to segment the image into small coherent clusters that are used to generate a refined superpixel...
With the increasing amount of image data available for cancer staging and diagnosis, it is clear that content-based image retrieval techniques are becoming more important to assist physicians in making diagnoses and tracking disease. Domain-specific feature descriptors have been previously shown to be effective in the retrieval of lung tumors. This work proposes a method to improve the rotation invariance...
In this paper, we propose a novel semi-supervised classification method for four types of lung nodules, i.e., well-circumscribed, vascularized, juxta-pleural and pleural-tail, in low dose computed tomography (LDCT) scans. The proposed method focuses on classifier design by incorporating the knowledge extracted from both training and testing datasets, and contains two stages: (1) bipartite graph construction,...
Microscopic cellular image segmentation has become one of the most important routine procedures in modern biological applications. The segmentation task is non-trivial, however, mainly due to imaging artifacts causing highly inhomogeneous appearances of cell nuclei and background with large intensity variations within and across images. Such inconsistent appearance profiles would cause feature overlapping...
In this paper, we propose a novel method for object localization, generally applicable to medical images in which the objects can be distinguished from the background mainly based on feature differences. We design a new CRF model with additional contrast and interest-region potentials, which encode the higher-order contextual information between regions, on the global and structural levels. We also...
This paper presents a framework for effective and fast content-based image retrieval for multi-modality PET-CT lung scans. PET-CT scans present significant advantages in tumor staging, but also place new challenges in computerized image analysis and retrieval. Our framework comprises 5 major components: lung field estimation, texture feature extraction, feature categorization, refinement using SVM,...
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