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This research focuses on the supramolecular challenge of enhancing multivalent binding between ligands and proteins or biological receptors on cell surfaces. Our special interest is using supramolecular-structured polymers, namely, polyrotaxanes consisting of ligand-immobilized -cyclodextrins (-CDs) threaded onto a poly(ethylene glycol) (PEG) chain capped at both terminals with bulky end groups via...
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