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Nanog is a core transcription factor specifically expressed not only in the pluripotent stem cells (PSCs), such as embryonic stem cells (ESCs), embryonic germ cells (EGCs), and induced PSCs (iPSCs), but also in the unipotent primordial germ cells (PGCs). Although Nanog promoter/enhancer regions are well characterized by in vitro analyses, direct correlations between the regulatory elements for Nanog...
Cover illustration: The cover image is based on the Technology Report Generation of Nanog reporter mice that distinguish pluripotent stem cells from unipotent primordial germ cells by Atsushi Suzuki et al., https://doi.org/10.1002/dvg.23334.
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