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Introduction: Cells stained by the Tcrb-V specific monoclonal antibody R78, which in LEW rats prevents Tcrb-V8.2 + T cell mediated EAE, display a polymorphism in the reactivity to superantigens (SEB and mtv-7 sag) and their frequency in the peripheral CD4 compartiment.Materials and Methods: Tcrb-V8.2 like gene segments of rat strains of different Tcrb haplotypes were amplified by PCR and RT-PCR,...
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