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A differential measurement design employing two nearly collinear optical beams can lead to surface plasmon polariton (SPP) sensors of increased dynamic range and signal-to-noise ratio. We demonstrate a differential measurement device that is based on wavelength interrogation, employs a single incident polarization state, and is combined with a 2-D nanohole array for operation at near-normal incidence,...
A transmission-based surface plasmon resonance (SPR) sensor for label-free detection of protein-carbohydrate and protein-protein binding proximate to a perforated gold surface is demonstrated. An SPR instrument makes real-time measurements of the resonant wavelength and/or the resonant angle of incidence of transmitted light; both are influenced by the presence of proteins at the gold surface-liquid...
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