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Recently, we reported the antiprotozoal activity of tetrahydropyridylidene ammonium salts. We inserted this motif into a fused ring system, a pyrido-benzodiazepine. The synthesis includes an enamine formation followed by a Mannich reaction to cyclic products and an S-methylation. The last step is a regioselective reduction process. All new compounds were characterized by UV–Vis spectroscopy, ATR FTIR...
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