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The imidazoline compound RX871024 reduces IL-1β-induced NO production thereby protecting against IL-1β-induced β-cell apoptosis. The aim of this study was to evaluate whether imidazolines RX871024 and efaroxan protect β-cells against death in the presence of a combination of the cytokines IL-1β, IFNγ, and TNFα. To address this issue, experiments involving different methods for detection of cell death,...
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