Search results for: D. Smith
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Differential Interactions of Cytochalasins with P-Glycoprotein
Oncology Research > 1995 > 7 > 9 > 435-443
Cytochalasins are a family of structurally related natural product cytotoxins that selectively depolymerize microfilaments. In this study, the interaction between several cytochalasins and the drug transporter P-glycoprotein was investigated. Dihydrocytochalasin B and cytochalasin E consistently sensitized P-glycoprotein-overexpressing human breast carcinoma cells (MCF-7/ADR) to daunomycin, vinblastine,...
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