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Cancer Immunotherapy
In article number 2200316, Dong Keun Han, Ik‐Hwan Kim, Wooram Park, and co‐workers present a combination therapy of metal‐phenolic network‐based immunoactive nanoparticles and bipolar irreversible electroporation (IRE) technology. A CpG‐oligodeoxynucleotides (CpG‐ODNs)‐coated Mn‐phenolic network nanoparticle efficiently primes antigen‐presenting cells to M1 polarization and proinflammatory...
To circumvent the limitations of conventional cancer immunotherapy, it is critical to prime antigen‐presenting cells (APCs) to initiate the cancer‐immune cycle. Here, the authors develop a metal‐phenolic network (MPN)‐based immunoactive nanoparticle in combination with irreversible electroporation (IRE) for an effective cancer immunotherapy. The MPN nanoparticles are synthesized by coordinating tannic...
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