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The epithelium is a thin layer of tissue that lines hollow organs, such as colon. Visualizing in vertical cross sections with sub-cellular resolution is essential to understanding early disease mechanisms that progress naturally in the plane perpendicular to the tissue surface. The dual axes confocal architecture collects optical sections in tissue by directing light at an angle incident to the surface...
We present an electrostatic MEMS scanner for a dual-axes confocal fluorescence endomicroscope to collect fluorescent images in three orthogonal planes of tissue with large field of view (FOV) at high frame rate. The scanner employs a novel lever-based dual-gimbal structure to perform coupling-free switchable XY/XZ/YZ two-dimensional (2D) beam scanning, and uses the parametric resonance excitation...
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