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British amyloid (ABri) peptide is precipitated as amyloid fibrils in pathological lesions which are characteristic of familial British dementia. Unlike for other amyloidogenic peptides which have been implicated in neurodegenerative disease, for example, Aβ in Alzheimer’s disease and α synuclein in Parkinson’s disease, nothing is yet known as to whether metals mediate the formation of ABri amyloid...
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