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A novel detection system was established previously for cells infected with the human cytomegalovirus (HCMV) in vitro that utilizes the unique IE1‐dependent nuclear dispersion of promyelocytic leukemia (PML) bodies early in the HCMV replication cycle. This assay system, designated “the PML assay,” makes use of the GFP‐PML‐expressing cell line SE/15, and allows real‐time monitoring of infected cells...
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