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Triggered release systems based on physiological stimuli have emerged for advanced therapeutic delivery applications. On page H273, Frank Caruso and co‐workers combine several independent release mechanisms that synergistically function to tune cargo release profi les. The simple and efficient synthesis allows the design of “smart” capsules with dual stimuliresponsive cargo release mechanisms for...
The assembly of responsive layer‐by‐layer‐assembled click polymer capsules that exhibit dual‐responsive cargo release mechanisms for the controlled release of cargo is reported. The capsules show reversible size changes between pH 6 and 7.4. The synergistic effects of pH and redox‐potential allow for rapid and efficient cargo release at simulated intracellular conditions.
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