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The present work aimed to investigate the effect of losartan treatment of healthy and diabetic rats on cardiomyocyte response to ATP depletion.Cells were isolated from normoglycemic (N) and streptozotocin-injected (55mg/kg) rats (D) treated or not treated with losartan (20mg/kg/day in the drinking water; NL and DL, respectively) for 3 weeks. In each group of cells, enzyme activities such as glucose-6-phosphate...
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