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A close association of smoking-associated lung cancer incidence with the Msp I and Ile-Val polymorphisms of CYP1A1 gene was found in a Japanese population in terms of genotype frequency comparison and cigarette dose response. A synergistic increase in susceptibility to lung cancer was observed when the susceptible genotypes of CYP1A1 were combined with a deficient GSTM1 genotype. Individual difference...
From January 1981 to December 1992, 248 patients with non-operable non-small cell lung cancer were treated by external radiotherapy (RT). Among these, 10 patients had Pancoast tumor with UICC clinical stage III (n=8) and IV (n=2) disease. Symptomatic relief, tumor response and survival were analyzed. As for initial symptoms, regional pain was observed in all patients, with arm pain being especially...
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