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The purpose of the present study was to investigate the expression and functional relevance of sarcolemmal L-type Ca 2+ -channels in failing and non-failing human myocardium. The protein expression of sarcolemmal L-type Ca 2+ -channels was determined with 3 H-(+)-PN 200-110-binding experiments and Western blot analysis using a specific antibody against theα 1 -subunit...
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