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Effects of Hochu-ekki-to (TJ-41) on the course of lethal rodent malarial infection with Plasmodium chabaudi AS were examined in male A/J mice. We examined the mortality, parasitemia and serum cytokines such as IL-12, IFN-γ and IL-4 in the infected and TJ-41-treated/infected mice. There was a significant difference in mortality between infected and treated/infected mice. A high mortality was observed...
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