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In this work we established three from altogether six proton dissociation constants (pKa) of hydroxyl groups of hypericin in its monomeric form. The monomeric state of hypericin (5.0×10−6mol·L−1) in aqueous solution was stabilised by the presence of hydrotropic drug Cromolyn disodium salt (6.0×10−2mol·L−1). Data show that one acid-base transition occurs with the pKa of 7.8 and the other two are characterised...
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