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Background/Aims: Nuclear factor (NF) κB activation plays a critical role in the initiation of liver growth after partial hepatectomy (PH). However, the issue of where specifically NF-κB is activated is unclear. We previously reported that heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a hepatotrophic factor. The aims of this study were to identify NF-κB-activated cells and...
Background/Aims: Recent work has shown that the signal transducer and activator of transcription (STAT) 3 activation is important for the initiation of the proliferative response following partial hepatectomy (PH). However, the issue of where STAT3 is activated and how it is regulated is unclear. The aims of this study were to identify STAT3-activated cells and to clarify the expression of suppressor...
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