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The various enantiomers of ketoprofen (S and R) and its racemic form (R/S) exhibited comparable phototoxicities when examined by the following in vitro test systems: (a) effects of pre-irradiated drugs on cultured hepatocytes; (b) co-irradiation of the drugs with hepatocytes or fibroblasts; (c) photohaemolysis sensitized by the various ketoprofen stereoisomers; (d) drug-photosensitized formation of...
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