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Modification of bovine serum albumin (BSA) by polyunsaturated fatty acids (PUFAs) under metal-catalyzed oxidation was investigated. It was found that the incubation of BSA and PUFAs for 72h led to the formation of high-molecular-weight proteins, lipofuscin-like fluorescent substances and protein carbonylation. The application of natural polyphenols (phloretin, epicatechin, quercetin and naringenin)...
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