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Kontrastmittel Eine allgemeine Strategie für die Entwicklung von bioorthogonalen fluorogenen Tetrazinsonden im fernen Rot‐ und nahen Infrarotbereich wird von Xiaogang Liu, Haoxing Wu et al. in ihrer Zuschrift vorgestellt (e202117386).
Bioorthogonal fluorogenic dyes are indispensable tools in wash‐free bioimaging of specific biological targets. However, the fluorogenicity of existing tetrazine‐based bioorthogonal probes deteriorates as the emission wavelength shifts towards the NIR window, greatly limiting their applications in live cells and tissues. Herein, we report a generalizable molecular design strategy to construct ultra‐fluorogenic...
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