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Objective
High‐fat diets cause obesity in male mice; however, the underlying mechanisms remain controversial. Here, three contrasting ideas were assessed: hedonic overdrive, reverse causality, and passive overconsumption models.
Methods
A total of 12 groups of 20 individually housed 12‐week‐old C57BL/6 male mice were exposed to 12 high‐fat diets with varying fat content from 40% to 80% (by calories),...