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Objective: A serotonergic dysfunction a reduction of P300 and more antisocial personality traits are supposed to characterize a subgroup of alcoholics with a high genetic load. A strong loudness dependence of N1/P2 auditory evoked-potentials (LDAEP) and MAO activity are discussed as indicators of central serotonergic neurotransmission. Patients with regard to family history of alcoholism (FHP, FHN)...
Objective: A serotonergic dysfunction a reduction of P300 and more antisocial personality traits are supposed to characterize a subgroup of alcoholics with a high genetic load. A strong loudness dependence of N1/P2 auditory evoked-potentials (LDAEP) and MAO activity are discussed as indicators of central serotonergic neurotransmission. Patients with regard to family history of alcoholism (FHP, FHN)...
Abnormalities of smooth pursuit eye movements (SPEM) are hypothesized to qualify as a genetic vulnerability marker for schizophrenia. We conducted a family study to further evaluate the familial specificity of SPEM dysfunction. A sample of 209 subjects (41 schizophrenia spectrum patients, 28 affective psychotics, 36 healthy first-degree relatives of schizophrenics, 17 healthy first-degree relatives...
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