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Ofloxacin (OFLX) is a known synthetic broad spectrum antibiotics which inhibit bacterial DNA topoisomerase activity. Previous studies showed reduced antimicrobial activity of photosensitized OFLX and its photo-products. Here, we have addressed the binding affinity of OFLX and its photo-products against DNA gyrase to measure the antimicrobial activity. Further, the study was extended to explore the...
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