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To improve the form-stability and lower the degradation rate of poly(trimethylene carbonate) (PTMC) in biomedical fields, the cross-linked PTMC networks (PTMC-Ns) with controllable properties were prepared via chemical cross-linking. We report higher gel percentage and lower swelling degree as well as enhanced thermal and mechanical properties of the PTMC-Ns by increasing the initial molecular weight...
The degradation behavior of P(TMC-co-CL) in different compositions was investigated via subcutaneous implantation in vivo. To clarify the role of enzymes in the degradation behavior of the copolymers, hydrolytic and enzymatic degradation were also performed. The mass loss, changes in molecular weight and polydispersity, as well as the variation in composition were monitored with degradation. The changes...
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