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Previously, we investigated the association between urinary cadmium (Cd) concentration and indicators of renal dysfunction, including total protein, β 2 -microglobulin (β 2 -MG), and N-acetyl-β-d-glucosaminidase (NAG). In 2778 inhabitants ⩾50 years of age (1114 men, 1664 women) in three different Cd nonpolluted areas in Japan, we showed that a dose–response relationship existed between...
Renal effects of cadmium exposure in people living in a cadmium-nonpolluted area in Japan were investigated. The population consisted of 1501 inhabitants (558 men and 743 women) over 50 years of age. Urinary cadmium was employed as an indicator of internal dose, and total urinary protein,β 2 -microglobulin andN-acetyl-β-glucosaminidase were used as indicators of renal dysfunction. Multiple...
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