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Objectives Left ventricular mass (LVM) at cardiac magnetic resonance imaging (CMR) is a frequent end point in clinical trials in nephrology. Trial participants with end stage renal disease (ESRD) may have a greater frequency of incidental findings (IF). We retrospectively investigated prevalence of IF in previous research CMR and reviewed their subsequent impact on participants. Methods Between...
Chronic kidney disease (CKD), as defined by low levels of eGFR, is common and is a risk factor for premature cardiovascular disease (CVD). The risk rises incrementally with decline in eGFR and is maximal in patients with end-stage kidney disease (ESKD) requiring dialysis (to around 20 times that of the general population). Conventional factors such as diabetes mellitus, hypertension, smoking and hyperlipidaemia...
Background Hyperphosphataemia is linked to cardiovascular disease and mortality in chronic kidney disease (CKD). Outcome in CKD is also affected by socioeconomic status. The objective of this study was to assess the associations between serum phosphate, multiple deprivation and outcome in CKD patients. Methods All adult patients currently not on renal replacement therapy (RRT), with first time attendance...
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