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Self‐folding is a rapidly evolving method for converting flat objects into three‐dimensional (3D) structures. However, because there are few materials with suitable properties, the application of self‐folding in tissue engineering has been hindered greatly. Herein, a novel self‐folding hydrogel using conformational transition mechanism is developed by employing photocrosslinkable silk fibroin and...
In this study, two types of BolA‐like amphiphilic peptides with dual ligands comprising a tumor‐targeting moiety of RGD sequence and a cell‐penetrating moiety of R8 sequence are designed and synthesized as gene vectors. The BolA‐structural peptide carriers can self‐assemble into spherical nanoparticles with a hydrophilic core and shell, which are similar to the viral capsid and can bind plasmid DNA...
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