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Understanding the interaction patterns among a set of biological entities in a pathway is an important exercise because it potentially could reveal the role of the entities in biological systems. Although a considerable amount of effort has been directed to the detection and mining of patterns in biological pathways in contemporary research, querying biological pathways remained relatively unexplored...
Epistasis usually contributes to many well known diseases making the traits more complex and harder to study. The interactions between multiple genes and their alleles of different loci often mask the effects of a single gene at particular locus resulting in a complex trait. So the analysis of epistasis uncovers the facts about the mechanisms and pathways involved in a disease by analyzing biological...
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